Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.

Arnold, A; Daum, S; von Winterfeld, M; Berg, E; Hummel, M; Horst, D; Rau, B; Stein, U; Treese, C

Arnold, A; Daum, S; von Winterfeld, M; Berg, E; Hummel, M; Horst, D; Rau, B; Stein, U; Treese, C.

Afiliação

Arnold A; Institute of Pathology, Charité - Universitätsmedizin Berlin, Germany. Electronic address: alexander.arnold@charite.de.
Daum S; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Charité - Universitätsmedizin, Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany.
von Winterfeld M; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Berg E; Institute of Pathology, Charité - Universitätsmedizin Berlin, Germany.
Hummel M; Institute of Pathology, Charité - Universitätsmedizin Berlin, Germany.
Horst D; Institute of Pathology, Charité - Universitätsmedizin Berlin, Germany.
Rau B; Department of Surgery, Campus Virchow-Klinikum and Campus Mitte, Charité - Universitätsmedizin, Berlin, Germany.
Stein U; Experimental and Clinical Research Center, Charité - Universitätsmedizin and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany.
Treese C; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Charité - Universitätsmedizin, Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany.

Pathol Res Pract ; 215(11): 152662, 2019 Nov.

Article em En | MEDLINE | ID: mdl-31575452

Assuntos

Adenocarcinoma/genética; Neoplasias Esofágicas/genética; Receptores Proteína Tirosina Quinases/genética; Neoplasias Gástricas/genética; Adenocarcinoma/enzimologia; Adulto; Idoso; Neoplasias Esofágicas/enzimologia; Feminino; Humanos; Imuno-Histoquímica; Masculino; Pessoa de Meia-Idade; Fusão Oncogênica; Receptores Proteína Tirosina Quinases/análise; Receptores Proteína Tirosina Quinases/biossíntese; Neoplasias Gástricas/enzimologia

Palavras-chave

Gastric and esophageal adenocarcinoma (AGE); Larotrectinib; Neurotrophic-tropomyosin receptor tyrosine kinase (NTRK) gene fusion

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Neoplasias Esofágicas / Adenocarcinoma / Receptores Proteína Tirosina Quinases Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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