Cutaneous polyarteritis nodosa in pediatric patients successfully treated with TNF-α inhibitor and methotrexate: Case series and literature review.
Pediatr Dermatol
; 36(6): 932-935, 2019 Nov.
Article
em En
| MEDLINE
| ID: mdl-31576593
ABSTRACT
Cutaneous polyarteritis nodosa (CPAN) is a rare necrotizing vasculitis affecting small- to medium-sized arteries. Reported treatments include oral corticosteroids alone or in combination with non-steroidal antiinflammatory drugs, intravenous immunoglobulins, cyclophosphamide, azathioprine, colchicine, or dapsone. However, some patients with CPAN do not respond to such treatments and continue to experience exacerbations over prolonged periods. This series provides support for the use of TNF-α inhibitors in the treatment of recalcitrant CPAN in pediatric patients.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Poliarterite Nodosa
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Metotrexato
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Fator de Necrose Tumoral alfa
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Fármacos Dermatológicos
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Infliximab
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Imunossupressores
Limite:
Adolescent
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Female
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Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article