Guidance for Studies Evaluating the Accuracy of Tuberculosis Triage Tests.
J Infect Dis
; 220(220 Suppl 3): S116-S125, 2019 10 08.
Article
em En
| MEDLINE
| ID: mdl-31593600
ABSTRACT
Approximately 3.6 million cases of active tuberculosis (TB) go potentially undiagnosed annually, partly due to limited access to confirmatory diagnostic tests, such as molecular assays or mycobacterial culture, in community and primary healthcare settings. This article provides guidance for TB triage test evaluations. A TB triage test is designed for use in people with TB symptoms and/or significant risk factors for TB. Triage tests are simple and low-cost tests aiming to improve ease of access and implementation (compared with confirmatory tests) and decrease the proportion of patients requiring more expensive confirmatory testing. Evaluation of triage tests should occur in settings of intended use, such as community and primary healthcare centers. Important considerations for triage test evaluation include study design, population, sample type, test throughput, use of thresholds, reference standard (ideally culture), and specimen flow. The impact of a triage test will depend heavily on issues beyond accuracy, primarily centered on implementation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Pulmonar
/
Bioensaio
/
Triagem
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Guias de Prática Clínica como Assunto
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Testes Diagnósticos de Rotina
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Mycobacterium tuberculosis
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Guideline
/
Incidence_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adult
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Child
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Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article