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Polygenic burden in focal and generalized epilepsies.
Leu, Costin; Stevelink, Remi; Smith, Alexander W; Goleva, Slavina B; Kanai, Masahiro; Ferguson, Lisa; Campbell, Ciaran; Kamatani, Yoichiro; Okada, Yukinori; Sisodiya, Sanjay M; Cavalleri, Gianpiero L; Koeleman, Bobby P C; Lerche, Holger; Jehi, Lara; Davis, Lea K; Najm, Imad M; Palotie, Aarno; Daly, Mark J; Busch, Robyn M; Lal, Dennis.
Afiliação
  • Leu C; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Stevelink R; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, Cambridge, MA, USA.
  • Smith AW; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London, UK.
  • Goleva SB; Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Kanai M; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, Cambridge, MA, USA.
  • Ferguson L; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA.
  • Campbell C; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
  • Kamatani Y; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, Cambridge, MA, USA.
  • Okada Y; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Sisodiya SM; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Cavalleri GL; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Koeleman BPC; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Lerche H; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Jehi L; Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Davis LK; Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Najm IM; Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Palotie A; The FutureNeuro Research Centre, Dublin 2, Ireland.
  • Daly MJ; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Busch RM; Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Lal D; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Brain ; 142(11): 3473-3481, 2019 11 01.
Article em En | MEDLINE | ID: mdl-31608925

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epilepsias Parciais / Epilepsia Generalizada / Herança Multifatorial Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epilepsias Parciais / Epilepsia Generalizada / Herança Multifatorial Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article