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Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.
Helsley, Robert N; Varadharajan, Venkateshwari; Brown, Amanda L; Gromovsky, Anthony D; Schugar, Rebecca C; Ramachandiran, Iyappan; Fung, Kevin; Kabbany, Mohammad Nasser; Banerjee, Rakhee; Neumann, Chase K; Finney, Chelsea; Pathak, Preeti; Orabi, Danny; Osborn, Lucas J; Massey, William; Zhang, Renliang; Kadam, Anagha; Sansbury, Brian E; Pan, Calvin; Sacks, Jessica; Lee, Richard G; Crooke, Rosanne M; Graham, Mark J; Lemieux, Madeleine E; Gogonea, Valentin; Kirwan, John P; Allende, Daniela S; Civelek, Mete; Fox, Paul L; Rudel, Lawrence L; Lusis, Aldons J; Spite, Matthew; Brown, J Mark.
Afiliação
  • Helsley RN; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Varadharajan V; Department of Internal Medicine, University of Cincinnati, Cincinnati, United States.
  • Brown AL; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Gromovsky AD; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Schugar RC; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Ramachandiran I; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Fung K; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Kabbany MN; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Banerjee R; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Neumann CK; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Finney C; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Pathak P; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Orabi D; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Osborn LJ; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Massey W; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Zhang R; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Kadam A; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Sansbury BE; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Pan C; Center for Experimental Therapeutics & Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, United States.
  • Sacks J; Department of Medicine, University of California, Los Angeles, Los Angeles, United States.
  • Lee RG; Department of Microbiology, University of California, Los Angeles, Los Angeles, United States.
  • Crooke RM; Department of Human Genetics, University of California, Los Angeles, Los Angeles, United States.
  • Graham MJ; Department of Pathobiology, Cleveland Clinic, Cleveland, United States.
  • Lemieux ME; Cardiovascular Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, United States.
  • Gogonea V; Cardiovascular Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, United States.
  • Kirwan JP; Cardiovascular Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, United States.
  • Allende DS; Bioinfo, Plantagenet, Canada.
  • Civelek M; Department of Chemistry, Cleveland State University, Cleveland, United States.
  • Fox PL; Department of Pathobiology, Cleveland Clinic, Cleveland, United States.
  • Rudel LL; Department of Anatomical Pathology, Cleveland Clinic, Cleveland, United States.
  • Lusis AJ; Department of Biomedical Engineering, University of Virginia, Charlottesville, United States.
  • Spite M; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, United States.
  • Brown JM; Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, United States.
Elife ; 82019 10 17.
Article em En | MEDLINE | ID: mdl-31621579
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aciltransferases / Hepatopatia Gordurosa não Alcoólica / Proteínas de Membrana / Obesidade Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aciltransferases / Hepatopatia Gordurosa não Alcoólica / Proteínas de Membrana / Obesidade Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article