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In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI.
Sager, Maximilian; Grimm, Michael; Aude, Philipp; Schick, Philipp; Merdivan, Simon; Hasan, Mahmoud; Kromrey, Marie-Luise; Sivert, Aurélien; Benameur, Hassan; Koziolek, Mirko; Tzvetkov, Mladen V; Weitschies, Werner.
Afiliação
  • Sager M; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Grimm M; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Aude P; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Schick P; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Merdivan S; Department of Pharmaceutical Biology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Hasan M; Department of Pharmaceutical Chemistry, Future University in Egypt, End of 90th road, Eltagamoa el-Kahmes, New Cairo, Cairo, Egypt; Department of Clinical Pharmacology, University Hospital Greifswald, Felix-Hausdorff-Straße 3, 17487, Greifswald, Germany.
  • Kromrey ML; Department of Diagnostic Radiology and Neuroradiology, University Hospital Greifswald, Ferdinand-Sauerbruch-Straße, D-17475, Greifswald, Germany.
  • Sivert A; Lonza R&D Center of Excellence, Rue Tobias Stimmer - BP 30442, 67412, Illkirch-Graffenstaden, France.
  • Benameur H; Lonza R&D Center of Excellence, Rue Tobias Stimmer - BP 30442, 67412, Illkirch-Graffenstaden, France.
  • Koziolek M; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany.
  • Tzvetkov MV; Department of Clinical Pharmacology, University Hospital Greifswald, Felix-Hausdorff-Straße 3, 17487, Greifswald, Germany.
  • Weitschies W; Department of Biopharmaceutics and Pharmaceutical Technology, Institute of Pharmacy, University of Greifswald, Felix-Hausdorff-Straße 3, D-17487, Greifswald, Germany. Electronic address: werner.weitschies@uni-greifswald.de.
J Control Release ; 313: 24-32, 2019 11 10.
Article em En | MEDLINE | ID: mdl-31626859
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saliva / Cafeína / Cápsulas / Portadores de Fármacos / Imageamento por Ressonância Magnética / Óxido Ferroso-Férrico Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saliva / Cafeína / Cápsulas / Portadores de Fármacos / Imageamento por Ressonância Magnética / Óxido Ferroso-Férrico Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article