Analysis of 5000â¯year-old human teeth using optimized large-scale and targeted proteomics approaches for detection of sex-specific peptides.
J Proteomics
; 211: 103548, 2020 01 16.
Article
em En
| MEDLINE
| ID: mdl-31626997
ABSTRACT
The study demonstrates the high potential of MS-based proteomics coupled to an iterative database search strategy for the in-depth investigation of ancient proteomes. An efficient targeted PRM MS-based approach, although limited to the detection of a single pair of sex-specific amelogenin peptides, allowed confirming the sex of individuals in ancient dental remains, an essential information for paleoanthropologists facing the issue of sex determination and dimorphism.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dente
/
Proteômica
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article