Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo.

Williams, Ruth M; Candido-Ferreira, Ivan; Repapi, Emmanouela; Gavriouchkina, Daria; Senanayake, Upeka; Ling, Irving T C; Telenius, Jelena; Taylor, Stephen; Hughes, Jim; Sauka-Spengler, Tatjana

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo.

Williams, Ruth M; Candido-Ferreira, Ivan; Repapi, Emmanouela; Gavriouchkina, Daria; Senanayake, Upeka; Ling, Irving T C; Telenius, Jelena; Taylor, Stephen; Hughes, Jim; Sauka-Spengler, Tatjana.

Afiliação

Williams RM; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Candido-Ferreira I; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Repapi E; University of Oxford, MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Oxford OX3 9DS, UK.
Gavriouchkina D; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Senanayake U; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Ling ITC; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK; University of Oxford, Department of Paediatric Surgery, Children's Hospital Oxford, Oxford, UK.
Telenius J; University of Oxford, MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Oxford OX3 9DS, UK; University of Oxford, MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Taylor S; University of Oxford, MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Oxford OX3 9DS, UK.
Hughes J; University of Oxford, MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Oxford OX3 9DS, UK; University of Oxford, MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK.
Sauka-Spengler T; University of Oxford, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, Oxford OX3 9DS, UK. Electronic address: tatjana.sauka-spengler@imm.ox.ac.uk.

Dev Cell ; 51(2): 255-276.e7, 2019 10 21.

Article em En | MEDLINE | ID: mdl-31639368

Assuntos

Regulação da Expressão Gênica no Desenvolvimento/genética; Redes Reguladoras de Genes/genética; Crista Neural/embriologia; Ativação Transcricional/genética; Animais; Heterogeneidade Genética; Vertebrados/genética

Palavras-chave

ATAC; Capture-C; chick; enhancers; gene regulatory network; neural crest; scATAC-seq; super-enhancers; transcription factors, scRNA-seq

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Regulação da Expressão Gênica no Desenvolvimento / Redes Reguladoras de Genes / Crista Neural Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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