Moderate vs high-load resistance training on muscular adaptations in rats.
Life Sci
; 238: 116964, 2019 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-31639398
ABSTRACT
AIMS:
The main aim of this study was to investigate the moderate versus high-load resistance training on muscle strength, hypertrophy and protein synthesis signaling in rats.METHODS:
Twenty rats were randomly allocated into three groups as follow control group (C, nâ¯=â¯6), high-load training (HL, nâ¯=â¯7) and moderate-load training (ML, nâ¯=â¯7). A ladder climb exercise was used to mimic resistance exercise. ML resistance training consisted of a moderate load, allowing performance at higher volume of load inherent to higher number of repetitions (8-16 climbing). HL resistance training consisted of progressively increase training load, with low volume of load (4-8 climbing). C group remained with physical activity restricted to their cage space. This experiment was conducted over a six-weeks period. Forty-eight hours after the last resistance training session the animals were euthanized for tissue collection.RESULTS:
Both HL and ML regimens promoted similar increases in muscle strength, elevated protein synthesis signaling demonstrated by increased skeletal muscle total/phosphorylated P-70S6K ratio and similar increases in plantaris and FHL muscle hypertrophy, all compared to control. All these similarities were demonstrated even though testosterone/cortisol ratio was higher in HL group compared to ML and control. ML regimen caused higher total training volume and soleus muscle hypertrophy, which was not demonstrated in HL group.CONCLUSION:
In conclusion, results suggest that both HL and ML induce muscle hypertrophy and increase on strength in a similar way. ML moreover seems to favor slow fiber hypertrophy due the higher training volume.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Condicionamento Físico Animal
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Adaptação Fisiológica
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Músculo Esquelético
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Força Muscular
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Treinamento Resistido
Limite:
Animals
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article