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Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies.
Lo, Chih Hung; Lim, Colin Kin-Wye; Ding, Zhipeng; Wickramasinghe, Sanjula P; Braun, Anthony R; Ashe, Karen H; Rhoades, Elizabeth; Thomas, David D; Sachs, Jonathan N.
Afiliação
  • Lo CH; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Lim CK; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Ding Z; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Wickramasinghe SP; Biochemistry and Molecular Biophysics Graduate Group, University of Pennsylvania, Philadelphia, PA, USA.
  • Braun AR; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Ashe KH; Department of Neurology, University of Minnesota, Minneapolis, MN, USA; Department of Neuroscience, University of Minnesota, Minneapolis, MN, USA; N. Bud Grossman Center for Memory Research and Care, University of Minnesota, Minneapolis, MN, USA; Geriatric Research, Education, and Clinical Centers,
  • Rhoades E; Biochemistry and Molecular Biophysics Graduate Group, University of Pennsylvania, Philadelphia, PA, USA; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.
  • Thomas DD; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA; Photonic Pharma LLC, Minneapolis, MN, USA.
  • Sachs JN; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA. Electronic address: jnsachs@umn.edu.
Alzheimers Dement ; 15(11): 1489-1502, 2019 11.
Article em En | MEDLINE | ID: mdl-31653529
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Proteínas tau / Tauopatias / Transferência Ressonante de Energia de Fluorescência / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Proteínas tau / Tauopatias / Transferência Ressonante de Energia de Fluorescência / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article