A Loop-Mediated Isothermal Amplification Assay Targeting Neisseria gonorrhoeae penA-60.001.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Article
em En
| MEDLINE
| ID: mdl-31658968
ABSTRACT
Ceftriaxone (CRO) is widely used as the first-line treatment for gonococcal infections. However, CRO-resistant Neisseria gonorrhoeae strains carrying mosaic penA-60.001 have emerged recently and disseminated worldwide. To meet the urgent need to detect these strains, we report here a loop-mediated isothermal amplification (LAMP) assay system that targets N. gonorrhoeaepenA-60.001. This assay system can differentiate N. gonorrhoeae strains carrying mosaic penA-60.001 from strains carrying other penA alleles.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ceftriaxona
/
Antibacterianos
/
Neisseria gonorrhoeae
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article