Construction and Characterization of a Mirror-Image l-DNA i-Motif.
Chembiochem
; 21(1-2): 94-97, 2020 01 15.
Article
em En
| MEDLINE
| ID: mdl-31659823
ABSTRACT
The first thermally stable and pH-responsive quadruplex intercalated motif (i-motif) structure formed by l-DNA is presented. Although this l-type i-motif exhibits the same physiochemical properties as its d isomer, its inverted chirality and good enzymatic resistance potentially open the way to the development of new DNA materials of pharmaceutical and biological interest.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
DNA
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article