Loss of ARID1A induces a stemness gene ALDH1A1 expression with histone acetylation in the malignant subtype of cholangiocarcinoma.

Yoshino, Jun; Akiyama, Yoshimitsu; Shimada, Shu; Ogura, Toshiro; Ogawa, Kosuke; Ono, Hiroaki; Mitsunori, Yusuke; Ban, Daisuke; Kudo, Atsushi; Yamaoka, Shoji; Tanabe, Minoru; Tanaka, Shinji

Yoshino, Jun; Akiyama, Yoshimitsu; Shimada, Shu; Ogura, Toshiro; Ogawa, Kosuke; Ono, Hiroaki; Mitsunori, Yusuke; Ban, Daisuke; Kudo, Atsushi; Yamaoka, Shoji; Tanabe, Minoru; Tanaka, Shinji.

Afiliação

Yoshino J; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Akiyama Y; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Shimada S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Ogura T; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Ogawa K; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Ono H; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Mitsunori Y; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Ban D; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Kudo A; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Yamaoka S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.
Tanabe M; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo.

Carcinogenesis ; 41(6): 734-742, 2020 07 10.

Article em En | MEDLINE | ID: mdl-31665232

Assuntos

Família Aldeído Desidrogenase 1/metabolismo; Neoplasias dos Ductos Biliares/patologia; Biomarcadores Tumorais/metabolismo; Colangiocarcinoma/patologia; Proteínas de Ligação a DNA/metabolismo; Histonas/metabolismo; Células-Tronco Neoplásicas/patologia; Retinal Desidrogenase/metabolismo; Fatores de Transcrição/metabolismo; Acetilação; Família Aldeído Desidrogenase 1/genética; Apoptose; Neoplasias dos Ductos Biliares/genética; Neoplasias dos Ductos Biliares/metabolismo; Biomarcadores Tumorais/genética; Movimento Celular; Proliferação de Células; Colangiocarcinoma/genética; Colangiocarcinoma/metabolismo; Proteínas de Ligação a DNA/genética; Feminino; Regulação Neoplásica da Expressão Gênica; Histona Desacetilase 1/genética; Histona Desacetilase 1/metabolismo; Histonas/genética; Humanos; Masculino; Pessoa de Meia-Idade; Células-Tronco Neoplásicas/metabolismo; Prognóstico; Retinal Desidrogenase/genética; Taxa de Sobrevida; Fatores de Transcrição/genética; Células Tumorais Cultivadas

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Células-Tronco Neoplásicas / Neoplasias dos Ductos Biliares / Histonas / Biomarcadores Tumorais / Colangiocarcinoma / Proteínas de Ligação a DNA / Retinal Desidrogenase / Família Aldeído Desidrogenase 1 Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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