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Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6.
De Vita, Elena; Smits, Niels; van den Hurk, Helma; Beck, Elizabeth M; Hewitt, Joanne; Baillie, Gemma; Russell, Emily; Pannifer, Andrew; Hamon, Véronique; Morrison, Angus; McElroy, Stuart P; Jones, Philip; Ignatenko, Natalia A; Gunkel, Nikolas; Miller, Aubry K.
Afiliação
  • De Vita E; Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Smits N; Faculty of Biosciences, University of Heidelberg, 69120, Heidelberg, Germany.
  • van den Hurk H; Pivot Park Screening Centre, Kloosterstraat 9, 5349 AB, Oss (The, Netherlands.
  • Beck EM; Pivot Park Screening Centre, Kloosterstraat 9, 5349 AB, Oss (The, Netherlands.
  • Hewitt J; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Baillie G; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Russell E; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Pannifer A; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Hamon V; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Morrison A; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • McElroy SP; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Jones P; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Ignatenko NA; European Screening Centre Newhouse (ESC) Biocity Scotland, Bo'ness Road, ML15UH, Newhouse, Scotland.
  • Gunkel N; University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85721, USA.
  • Miller AK; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85721, USA.
ChemMedChem ; 15(1): 79-95, 2020 01 07.
Article em En | MEDLINE | ID: mdl-31675166

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calicreínas / Fármacos Neuroprotetores / Oxazolidinonas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Calicreínas / Fármacos Neuroprotetores / Oxazolidinonas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article