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Rapid maturation of the hepatic cell line Huh7 via CDK inhibition for PXR dependent CYP450 metabolism and induction.
Bulutoglu, Beyza; Mert, Safak; Rey-Bedón, Camilo; Deng, Sarah L; Yarmush, Martin L; Usta, O Berk.
Afiliação
  • Bulutoglu B; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospitals for Children, Boston, MA, 02114, USA.
  • Mert S; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospitals for Children, Boston, MA, 02114, USA.
  • Rey-Bedón C; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospitals for Children, Boston, MA, 02114, USA.
  • Deng SL; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospitals for Children, Boston, MA, 02114, USA.
  • Yarmush ML; Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospitals for Children, Boston, MA, 02114, USA. ireis@sbi.org.
  • Usta OB; Department of Biomedical Engineering, Rutgers University, Piscataway, NJ, 08854, USA. ireis@sbi.org.
Sci Rep ; 9(1): 15848, 2019 11 01.
Article em En | MEDLINE | ID: mdl-31676845
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rifampina / Sistema Enzimático do Citocromo P-450 / Receptor de Pregnano X / Amiodarona / Fígado Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rifampina / Sistema Enzimático do Citocromo P-450 / Receptor de Pregnano X / Amiodarona / Fígado Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article