Your browser doesn't support javascript.
loading
Targeting miRNAs by polyphenols: Novel therapeutic strategy for aging.
Majidinia, Maryam; Karimian, Ansar; Alemi, Forough; Yousefi, Bahman; Safa, Amin.
Afiliação
  • Majidinia M; Solid Tumor Research Center, Urmia University of Medical Sciences, Urmia, Iran.
  • Karimian A; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; Student Research Committee, Babol University of medical sciences, Babol, Iran; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Alemi F; Molecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Yousefi B; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: yousefib@tbzmed.ac.ir.
  • Safa A; Institute of Research and Development, Duy Tan University, Da Nang 550000, Viet Nam. Electronic address: aminsafa@duytan.edu.vn.
Biochem Pharmacol ; 173: 113688, 2020 03.
Article em En | MEDLINE | ID: mdl-31682793
ABSTRACT
Regarding the importance of genetic and epigenetic factors in regulation of aging process, different expression pattern of non-coding RNAs in aging could be investigated. Accordingly, micro RNAs (miRNAs) with a wide range of physiological functions as well as a significant footprint in many diseases have been demonstrated to be down or upregulated during the aging process. Therefore, age-associated microRNAs and their targets have potentially detected the accelerated aging and predicted the risks for age-related diseases. Polyphenols as important antioxidants in human dietary observed in fruits and some beverages have beneficial effects on longevity and aging. Considering miRNAs as an interesting mediator in modulating polyphenols' biological effects, targeting miRNAs which is using polyphenols could be a novel strategy for aging.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Regulação da Expressão Gênica / MicroRNAs / Polifenóis / Longevidade Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Regulação da Expressão Gênica / MicroRNAs / Polifenóis / Longevidade Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article