Disruption of a putative mitochondrial oxaloacetate shuttle protein in Aspergillus carbonarius results in secretion of malic acid at the expense of citric acid production.

Yang, Lei; Linde, Tore; Hossain, Abeer H; Lübeck, Mette; Punt, Peter J; Lübeck, Peter S

Yang, Lei; Linde, Tore; Hossain, Abeer H; Lübeck, Mette; Punt, Peter J; Lübeck, Peter S.

Afiliação

Yang L; Department of Chemistry and Bioscience, Section for Sustainable Biotechnology, Aalborg University, A.C. Meyers Vaenge 15, DK-2450, Copenhagen, SV, Denmark.
Linde T; Department of Chemistry and Bioscience, Section for Sustainable Biotechnology, Aalborg University, A.C. Meyers Vaenge 15, DK-2450, Copenhagen, SV, Denmark.
Hossain AH; Present address: AGC Biologics, Vandtaarnsvej 83B, DK-2860, Soeborg, Copenhagen, Denmark.
Lübeck M; Dutch DNA Biotech BV, Padualaan 8, 3584CH, Utrecht, The Netherlands.
Punt PJ; Department of Chemistry and Bioscience, Section for Sustainable Biotechnology, Aalborg University, A.C. Meyers Vaenge 15, DK-2450, Copenhagen, SV, Denmark.
Lübeck PS; Dutch DNA Biotech BV, Padualaan 8, 3584CH, Utrecht, The Netherlands.

BMC Biotechnol ; 19(1): 72, 2019 11 04.

Article em En | MEDLINE | ID: mdl-31684928

Assuntos

Aspergillus/metabolismo; Ácido Cítrico/metabolismo; Engenharia Metabólica/métodos; Proteínas Mitocondriais/metabolismo; Oxaloacetatos/metabolismo; Malatos/metabolismo

Palavras-chave

Aspergillus carbonarius; Citric acid; Malic acid; Metabolic engineering; Mitochondrial transport protein

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxaloacetatos / Aspergillus / Ácido Cítrico / Proteínas Mitocondriais / Engenharia Metabólica Tipo de estudo: Health_economic_evaluation Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google