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A Phase I Study of ADCT-402 (Loncastuximab Tesirine), a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma.
Kahl, Brad S; Hamadani, Mehdi; Radford, John; Carlo-Stella, Carmelo; Caimi, Paolo; Reid, Erin; Feingold, Jay M; Ardeshna, Kirit M; Solh, Melhem; Heffner, Leonard T; Ungar, David; He, Shui; Boni, Joseph; Havenith, Karin; O'Connor, Owen A.
Afiliação
  • Kahl BS; Department of Medicine, Oncology Division, Washington University, St. Louis, Missouri. bkahl@wustl.edu.
  • Hamadani M; Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin.
  • Radford J; NIHR Experimental Cancer Medicine Centre, The Christie NHS Foundation Trust and University of Manchester, Manchester, United Kingdom.
  • Carlo-Stella C; Department of Medical Oncology and Hematology, Humanitas Clinical and Research Center, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS, Rozzano, Milan, Italy
  • Caimi P; Case Western Reserve, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
  • Reid E; Division of Hematology/Oncology, University of California San Diego Moores Cancer Center, La Jolla, California.
  • Feingold JM; ADC Therapeutics America Inc., Murray Hill, New Jersey.
  • Ardeshna KM; Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
  • Solh M; Blood and Marrow Transplant Program at Northside Hospital, Atlanta, Georgia.
  • Heffner LT; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
  • Ungar D; ADC Therapeutics America Inc., Murray Hill, New Jersey.
  • He S; ADC Therapeutics America Inc., Murray Hill, New Jersey.
  • Boni J; ADC Therapeutics America Inc., Murray Hill, New Jersey.
  • Havenith K; ADC Therapeutics (UK) Limited, London, United Kingdom.
  • O'Connor OA; Center for Lymphoid Malignancies, Columbia University Medical Center, The New York Presbyterian Hospital, New York, New York.
Clin Cancer Res ; 25(23): 6986-6994, 2019 12 01.
Article em En | MEDLINE | ID: mdl-31685491
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Benzodiazepinas / Linfoma de Células B / Imunoconjugados / Antígenos CD19 / Anticorpos Monoclonais Humanizados / Anticorpos Monoclonais / Recidiva Local de Neoplasia / Antineoplásicos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Benzodiazepinas / Linfoma de Células B / Imunoconjugados / Antígenos CD19 / Anticorpos Monoclonais Humanizados / Anticorpos Monoclonais / Recidiva Local de Neoplasia / Antineoplásicos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article