The Mutational Features of Aristolochic Acid-Induced Mouse and Human Liver Cancers.

Lu, Zhao-Ning; Luo, Qing; Zhao, Li-Nan; Shi, Yi; Wang, Na; Wang, Lan; Han, Ze-Guang

Lu, Zhao-Ning; Luo, Qing; Zhao, Li-Nan; Shi, Yi; Wang, Na; Wang, Lan; Han, Ze-Guang.

Afiliação

Lu ZN; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Luo Q; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Zhao LN; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Shi Y; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Wang N; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Wang L; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Han ZG; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.

Hepatology ; 71(3): 929-942, 2020 03.

Article em En | MEDLINE | ID: mdl-31692012

Assuntos

Ácidos Aristolóquicos/toxicidade; Neoplasias Hepáticas/induzido quimicamente; Neoplasias Hepáticas/genética; Mutação; Animais; Neoplasias dos Ductos Biliares/induzido quimicamente; Neoplasias dos Ductos Biliares/genética; Tetracloreto de Carbono/toxicidade; Carcinoma Hepatocelular/induzido quimicamente; Carcinoma Hepatocelular/genética; Colangiocarcinoma/induzido quimicamente; Colangiocarcinoma/genética; Dano ao DNA; Relação Dose-Resposta a Droga; Humanos; Janus Quinase 1/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Proteína Supressora de Tumor p53/genética; Quinases raf/fisiologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Aristolóquicos / Neoplasias Hepáticas / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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