Running the Light: Nucleotide Metabolism Drives Bypass of Senescence in Cancer.

Halbrook, Christopher J; Wahl, Daniel R; Lyssiotis, Costas A

Halbrook, Christopher J; Wahl, Daniel R; Lyssiotis, Costas A.

Afiliação

Halbrook CJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Wahl DR; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA. Electronic address: clyssiot@med.umich.edu.

Trends Biochem Sci ; 44(12): 991-993, 2019 12.

Article em En | MEDLINE | ID: mdl-31699584

Assuntos

Senescência Celular; Neoplasias/genética; Humanos; Alvo Mecanístico do Complexo 1 de Rapamicina; Nucleotídeos; Oncogenes

Palavras-chave

RPIA; mTORC1; nucleotide metabolism; p16; pentose phosphate pathway

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Senescência Celular / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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