The Functional Significance of Endocrine-immune Interactions in Health and Disease.
Curr Protein Pept Sci
; 21(1): 52-65, 2020.
Article
em En
| MEDLINE
| ID: mdl-31702489
ABSTRACT
Hormones are known to influence various body systems that include skeletal, cardiac, digestive, excretory, and immune systems. Emerging investigations suggest the key role played by secretions of endocrine glands in immune cell differentiation, proliferation, activation, and memory attributes of the immune system. The link between steroid hormones such as glucocorticoids and inflammation is widely known. However, the role of peptide hormones and amino acid derivatives such as growth and thyroid hormones, prolactin, dopamine, and thymopoietin in regulating the functioning of the immune system remains unclear. Here, we reviewed the findings pertinent to the functional role of hormone-immune interactions in health and disease and proposed perspective directions for translational research in the field.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prolactina
/
Hormônio do Crescimento
/
Doenças do Sistema Endócrino
/
Sistema Endócrino
/
Timócitos
/
Sistema Imunitário
/
Doenças do Sistema Imunitário
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article