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Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial.
Marston, Nicholas A; Kamanu, Frederick K; Nordio, Francesco; Gurmu, Yared; Roselli, Carolina; Sever, Peter S; Pedersen, Terje R; Keech, Anthony C; Wang, Huei; Lira Pineda, Armando; Giugliano, Robert P; Lubitz, Steven A; Ellinor, Patrick T; Sabatine, Marc S; Ruff, Christian T.
Afiliação
  • Marston NA; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.A.M., F.K.K., F.N., Y.G., R.P.G., M.S.S., C.T.R.).
  • Kamanu FK; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.A.M., F.K.K., F.N., Y.G., R.P.G., M.S.S., C.T.R.).
  • Nordio F; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.A.M., F.K.K., F.N., Y.G., R.P.G., M.S.S., C.T.R.).
  • Gurmu Y; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.A.M., F.K.K., F.N., Y.G., R.P.G., M.S.S., C.T.R.).
  • Roselli C; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard Cambridge, MA (C.R., S.A.L., P.T.E.).
  • Sever PS; University Medical Center Groningen, University of Groningen, the Netherlands (C.R.).
  • Pedersen TR; National Heart and Lung Institute, Imperial College London, United Kingdom (P.S.S.).
  • Keech AC; Oslo University Hospital, Ulleval and Medical Faculty, University of Oslo, Norway (T.R.P.).
  • Wang H; Sydney Medical School, National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Australia (A.C.K.).
  • Lira Pineda A; Amgen, Thousand Oaks, CA (H.W., A.L.P.).
  • Giugliano RP; Amgen, Thousand Oaks, CA (H.W., A.L.P.).
  • Lubitz SA; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (N.A.M., F.K.K., F.N., Y.G., R.P.G., M.S.S., C.T.R.).
  • Ellinor PT; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard Cambridge, MA (C.R., S.A.L., P.T.E.).
  • Sabatine MS; Cardiovascular Research Center, Massachusetts General Hospital, Boston (S.A.L., P.T.E.).
  • Ruff CT; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard Cambridge, MA (C.R., S.A.L., P.T.E.).
Circulation ; 141(8): 616-623, 2020 02 25.
Article em En | MEDLINE | ID: mdl-31707849
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / Anticolesterolemiantes Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / Anticolesterolemiantes Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article