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Clofibrate, a PPAR-α agonist, abrogates sodium fluoride-induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba-1/anti-calbindin signaling pathways.
Oyagbemi, Ademola A; Adebiyi, Olamide E; Adigun, Kabirat O; Ogunpolu, Blessing S; Falayi, Olufunke O; Hassan, Fasilat O; Folarin, Oluwabusayo R; Adebayo, Adedeji K; Adejumobi, Olumuyiwa A; Asenuga, Ebunoluwa R; Ola-Davies, Olufunke E; Omobowale, Temidayo O; Olopade, James O; Saba, Adebowale B; Adedapo, Adeolu A; Nkadimeng, Sanah M; McGaw, Lyndy J; Oguntibeju, Oluwafemi O; Yakubu, Momoh A.
Afiliação
  • Oyagbemi AA; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Adebiyi OE; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Adigun KO; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Ogunpolu BS; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Falayi OO; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Hassan FO; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Folarin OR; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Benin, Nigeria.
  • Adebayo AK; Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria.
  • Adejumobi OA; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Asenuga ER; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Ola-Davies OE; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Benin, Nigeria.
  • Omobowale TO; Department of Veterinary Anatomy, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Olopade JO; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Saba AB; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Adedapo AA; Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria.
  • Nkadimeng SM; Department of Veterinary Anatomy, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • McGaw LJ; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Oguntibeju OO; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria.
  • Yakubu MA; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Faculty of Veterinary Science, Onderstepoort, South Africa.
Environ Toxicol ; 35(2): 242-253, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31710167
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataxia / Fluoreto de Sódio / Proteínas de Ligação ao Cálcio / Clofibrato / Estresse Oxidativo / Fármacos Neuroprotetores / PPAR alfa / Calbindinas / Proteína Glial Fibrilar Ácida / Proteínas dos Microfilamentos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ataxia / Fluoreto de Sódio / Proteínas de Ligação ao Cálcio / Clofibrato / Estresse Oxidativo / Fármacos Neuroprotetores / PPAR alfa / Calbindinas / Proteína Glial Fibrilar Ácida / Proteínas dos Microfilamentos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article