Endoplasmic reticulum stress differentially inhibits endoplasmic reticulum and inner nuclear membrane protein quality control degradation pathways.

Buchanan, Bryce W; Mehrtash, Adrian B; Broshar, Courtney L; Runnebohm, Avery M; Snow, Brian J; Scanameo, Laura N; Hochstrasser, Mark; Rubenstein, Eric M

Buchanan, Bryce W; Mehrtash, Adrian B; Broshar, Courtney L; Runnebohm, Avery M; Snow, Brian J; Scanameo, Laura N; Hochstrasser, Mark; Rubenstein, Eric M.

Afiliação

Buchanan BW; Department of Biology, Ball State University, Muncie, Indiana 47306.
Mehrtash AB; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520.
Broshar CL; Department of Biology, Ball State University, Muncie, Indiana 47306.
Runnebohm AM; Department of Biology, Ball State University, Muncie, Indiana 47306.
Snow BJ; Department of Biology, Ball State University, Muncie, Indiana 47306.
Scanameo LN; Department of Biology, Ball State University, Muncie, Indiana 47306.
Hochstrasser M; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520.
Rubenstein EM; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520.

J Biol Chem ; 294(51): 19814-19830, 2019 12 20.

Article em En | MEDLINE | ID: mdl-31723032

Assuntos

Núcleo Celular/metabolismo; Estresse do Retículo Endoplasmático; Retículo Endoplasmático/metabolismo; Membrana Nuclear/metabolismo; Animais; Bovinos; Regulação Fúngica da Expressão Gênica; Manosil-Glicoproteína Endo-beta-N-Acetilglucosaminidase/química; Proteínas de Membrana/metabolismo; Proteínas de Membrana Transportadoras/metabolismo; Metaloendopeptidases/metabolismo; Monoéster Fosfórico Hidrolases/metabolismo; Plasmídeos/metabolismo; Transporte Proteico; Desdobramento de Proteína; Proteólise; Saccharomyces cerevisiae/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

E3 ubiquitin ligase; Saccharomyces cerevisiae; Ste24; endoplasmic reticulum stress (ER stress); endoplasmic reticulumassociated protein degradation (ERAD); inner nuclear membrane-associated degradation (INMAD); protein quality control; protein translocation; translocon; yeast genetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Núcleo Celular / Retículo Endoplasmático / Estresse do Retículo Endoplasmático / Membrana Nuclear Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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