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Hanging donor lungs give good short-, mid- and long-term results in lung transplantation.
De Wolf, Julien; Renard, Regis; Lehouerou, Thomas; Glorion, Matthieu; Pricopi, Ciprian; Bonnette, Pierre; Parquin, Francois; Roux, Antoine; Leguen, Morgan; Chapelier, Alain; Sage, Edouard.
Afiliação
  • De Wolf J; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Renard R; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Lehouerou T; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Glorion M; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Pricopi C; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Bonnette P; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Parquin F; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Roux A; Department of Pneumology, Foch Hospital, Suresnes, France.
  • Leguen M; Department of Anaesthesiology, Foch Hospital, Suresnes, France.
  • Chapelier A; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
  • Sage E; Thoracic Surgery and Lung Transplantation Department, Foch Hospital, Suresnes, France.
Clin Transplant ; 34(1): e13758, 2020 01.
Article em En | MEDLINE | ID: mdl-31758578
ABSTRACT

BACKGROUND:

Hanging donors are considered as marginal donors and frequently unsuitable for lung transplantation. However, there is no evidence of higher lung transplantation (LTx) morbidity-mortality with lungs providing by hanging donor.

METHODS:

Between January 2010 and July 2015, we performed a retrospective study at Foch hospital. We aimed to assess whether hanging donor grafts are suitable for lung transplantation.

RESULTS:

A total of 299 LTx were performed. Subjects were allocated to a hanging group (HG) (n = 20) and a control group (CG) (n = 279). Donor and recipient characteristics did not differ. Primary graft dysfunction (PGD) at 72 hours was comparable in both groups (P = .75). The median duration of postoperative mechanical ventilation (1 [range, 0-84] vs 1 [range, 0-410] day, P = .35), the hospital length of stay (31 days [20-84] vs 32 days [12-435], P = .36) did not differ between the two groups. No statistically significant difference was found in 1-year and 5-year survival between the HG (83% and 78%) and the CG (86% and 75%), P = .85.

CONCLUSION:

We believe that hanging donors should be considered as conventional donors with particular caution in the final evaluation of the graft and in perioperative management.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Pulmão Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Pulmão Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article