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Hepatic actinomycosis - A potential mimicker of malignancy.
Murphy, Patrick; Mar, Winnie A; Allison, David; Cornejo, Gabriela Aguiluz; Setty, Suman; Giulianotti, Pier Cristoforo.
Afiliação
  • Murphy P; University of Illinois at Chicago, Department of Radiology, 1740 W Taylor St, Rm 2483, (MC 931), Chicago, IL 60612, USA.
  • Mar WA; University of Illinois at Chicago, Department of Radiology, 1740 W Taylor St, Rm 2483, (MC 931), Chicago, IL 60612, USA.
  • Allison D; University of Illinois at Chicago, Department of Pathology, 840 S. Wood St, Ste 130 CSN (MC 847), Chicago, IL 60612, USA.
  • Cornejo GA; University of Illinois at Chicago, Department of Surgery, 840 South Wood St, Ste 376 CSN (MC 958), Chicago, IL 60612, USA.
  • Setty S; University of Illinois at Chicago, Department of Pathology, 840 S. Wood St, Ste 130 CSN (MC 847), Chicago, IL 60612, USA.
  • Giulianotti PC; University of Illinois at Chicago, Department of Surgery, 840 South Wood St, Ste 376 CSN (MC 958), Chicago, IL 60612, USA.
Radiol Case Rep ; 15(2): 105-109, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31762867
Actinomycosis is a rare granulomatous disease caused by commensal bacteria (Actinomycetaceae family) of the oropharynx, gastrointestinal, and urogenital tract. Infection most commonly involves the cervicofacial region but less frequently the abdominal region, typically secondary to a disruption of normal gastrointestinal mucosa. We present a patient with vague symptoms of fevers and myalgias and a recent diagnosis of rectal cancer. On CT, there were multiple centrally hypoattenuating hepatic lesions suspicious for metastasis vs abscesses, also confirmed by ultrasound. Initial image guided biopsy was non-diagnostic. Laparoscopic resection of one of the hepatic lesions showed pus consistent with an abscess. No organisms were identified by culture and a sample was sent to an outside laboratory for genomic polymerase chain reaction (PCR) analysis where Actinomyces DNA was isolated. This case report highlights a rare presentation of primary hepatic Actinomycosis and some of the challenges in diagnosing Actinomycosis due to its variable clinical and radiological manifestations and lack of diagnostic sensitivity by traditional microscopy and culture based techniques.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article