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Acetylation changes tau interactome to degrade tau in Alzheimer's disease animal and organoid models.
Choi, Heesun; Kim, Haeng Jun; Yang, Jinhee; Chae, Sehyun; Lee, Wonik; Chung, Sunwoo; Kim, Jisoo; Choi, Hyunjung; Song, Hyeseung; Lee, Chang Kon; Jun, Jae Hyun; Lee, Yong Jae; Lee, Kyunghyeon; Kim, Semi; Sim, Hye-Ri; Choi, Young Il; Ryu, Keun Ho; Park, Jong-Chan; Lee, Dongjoon; Han, Sun-Ho; Hwang, Daehee; Kyung, Jangbeen; Mook-Jung, Inhee.
Afiliação
  • Choi H; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Kim HJ; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Yang J; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Chae S; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Lee W; Center for Plant Aging Research, Institute for Basic Science, DGIST, Daegu, Korea.
  • Chung S; Korea Brain Bank, Korea Brain Research Institute, Daegu, Korea.
  • Kim J; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Choi H; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Song H; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Lee CK; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Jun JH; Interdisciplinary Graduate Program in Genetic Engineering, Seoul National University, Seoul, Korea.
  • Lee YJ; Department of Medicinal Chemistry, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Lee K; Department of Medicinal Chemistry, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Kim S; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Sim HR; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Choi YI; Department of Nonclinical Development, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Ryu KH; Department of Nonclinical Development, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Park JC; Department of Nonclinical Development, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Lee D; Department of Pharmacology, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Han SH; Department of Nonclinical Development, CKD Research Institute, CKD Pharmaceutical Company, Seoul, Korea.
  • Hwang D; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Kyung J; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
  • Mook-Jung I; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea.
Aging Cell ; 19(1): e13081, 2020 01.
Article em En | MEDLINE | ID: mdl-31763743
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Proteínas tau / Doenças Neurodegenerativas / Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Proteínas tau / Doenças Neurodegenerativas / Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article