The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-&#954;B Activation.

Carpi, Sara; Scoditti, Egeria; Massaro, Marika; Polini, Beatrice; Manera, Clementina; Digiacomo, Maria; Esposito Salsano, Jasmine; Poli, Giulio; Tuccinardi, Tiziano; Doccini, Stefano; Santorelli, Filippo Maria; Carluccio, Maria Annunziata; Macchia, Marco; Wabitsch, Martin; De Caterina, Raffaele; Nieri, Paola

The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation.

Carpi, Sara; Scoditti, Egeria; Massaro, Marika; Polini, Beatrice; Manera, Clementina; Digiacomo, Maria; Esposito Salsano, Jasmine; Poli, Giulio; Tuccinardi, Tiziano; Doccini, Stefano; Santorelli, Filippo Maria; Carluccio, Maria Annunziata; Macchia, Marco; Wabitsch, Martin; De Caterina, Raffaele; Nieri, Paola.

Afiliação

Carpi S; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Scoditti E; Interdepartmental Research Center "Nutraceuticals and Food for Health" University of Pisa, 56124 Pisa, Italy.
Massaro M; National Research Council (CNR) Institute of Clinical Physiology (IFC), 73100 Lecce, Italy.
Polini B; National Research Council (CNR) Institute of Clinical Physiology (IFC), 73100 Lecce, Italy.
Manera C; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Digiacomo M; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Esposito Salsano J; Interdepartmental Research Center "Nutraceuticals and Food for Health" University of Pisa, 56124 Pisa, Italy.
Poli G; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Tuccinardi T; Interdepartmental Research Center "Nutraceuticals and Food for Health" University of Pisa, 56124 Pisa, Italy.
Doccini S; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Santorelli FM; Doctoral School in Life Sciences, University of Siena, 53100 Siena, Italy.
Carluccio MA; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Macchia M; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Wabitsch M; Molecular Medicine for Neurodegenerative and Neuromuscular Diseases Unit, IRCCS Fondazione Stella Maris, Calambrone, 56128 Pisa, Italy.
De Caterina R; Molecular Medicine for Neurodegenerative and Neuromuscular Diseases Unit, IRCCS Fondazione Stella Maris, Calambrone, 56128 Pisa, Italy.
Nieri P; National Research Council (CNR) Institute of Clinical Physiology (IFC), 73100 Lecce, Italy.

Nutrients ; 11(12)2019 Nov 21.

Article em En | MEDLINE | ID: mdl-31766503

Assuntos

Adipócitos/efeitos dos fármacos; Aldeídos/farmacologia; Monoterpenos Ciclopentânicos/farmacologia; Inflamação/metabolismo; NF-kappa B/metabolismo; Fenóis/farmacologia; Adipócitos/metabolismo; Células Cultivadas; Exossomos; Regulação da Expressão Gênica/efeitos dos fármacos; Humanos; Inflamação/genética; MicroRNAs/análise; MicroRNAs/genética; MicroRNAs/metabolismo; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

NF-κB; adipocyte; exosome; extra-virgin olive oil; gene expression; inflammation; miRNA; obesity; oleacein; oleocanthal

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenóis / NF-kappa B / Adipócitos / Aldeídos / Monoterpenos Ciclopentânicos / Inflamação Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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