Triacontanoic ester of 5''-hydroxyjustisolin: Tumour suppressive role in cervical cancer via Bcl-2, BAX and caspase-3 mediated signalling.

Joseph, Litty; Srinivasan, K K.

Afiliação

Joseph L; Department of Pharmaceutical Sciences, Centre for Professional and Advanced studies, Cheruvandoor Campus, Ettumanoor PO, Kottayam, 686 631, Kerala, India.
Srinivasan KK; Department of Chemistry, Shri Madhwa Vadiraja Institute of Technology and Management, Bantakal, Udupi, 574 115, Karnataka, India.

Toxicol Rep ; 6: 1198-1205, 2019.

Article em En | MEDLINE | ID: mdl-31768331

Palavras-chave

Antitumor; BAX; Bcl-2; Caspase-3; DLA, Daltons lymphoma ascites; DMEM, Dulbecco's modified eagle's medium; DMSO, dimethyl suphoxide; FBS, fetal bovine serum; HaCat, human keratinocyte immortalised; HeLa, human cervical carcinoma; Justicia simplex D. Don; MCF-7, human breast adenocarcinoma cell line; MTT, methyl tetrazolium assay; RT-PCR, reverse transcriptase polymerize chain reaction; TE5-OHJ, triacontanoic ester of 5Ê¹Ê¹-hydroxyjustisolin; Triacontanoic ester of 5Êº -hydroxyjustisolin

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article