Versatile symport transporters based on cyclic peptide dimers.
Chem Commun (Camb)
; 56(1): 46-49, 2019 Dec 17.
Article
em En
| MEDLINE
| ID: mdl-31768506
ABSTRACT
We present the synthesis and transmembrane transport properties of a new family of tris-pyridine-decorated cyclic peptides. These molecules are designed to self-assemble into dimeric shuttles in nonpolar media, which act as symport ionophores in which, apparently, the tris-pyridine scaffold complexes both cations and anions with high potency and efficacy.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Peptídeos Cíclicos
/
Piridinas
/
Lipossomas Unilamelares
/
Ionóforos
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Bicamadas Lipídicas
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article