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Advanced glycation end products are associated with sarcopenia in older women: aging marker dynamics.
Eguchi, Yawara; Toyoguchi, Toru; Inage, Kazuhide; Fujimoto, Kazuki; Orita, Sumihisa; Suzuki, Miyako; Kanamoto, Hirohito; Abe, Koki; Norimoto, Masaki; Umimura, Tomotaka; Koda, Masao; Furuya, Takeo; Aoki, Yasuchika; Nakamura, Junichi; Akazawa, Tsutomu; Takahashi, Kazuhisa; Ohtori, Seiji.
Afiliação
  • Eguchi Y; Department of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.
  • Toyoguchi T; Department of Orthopaedic Surgery, Chiba Qiball clinic, Chuo-ku, Japan.
  • Inage K; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Fujimoto K; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Orita S; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Suzuki M; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Kanamoto H; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Abe K; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Norimoto M; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Umimura T; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Koda M; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Furuya T; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Aoki Y; Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan.
  • Nakamura J; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Akazawa T; Department of Orthopaedic Surgery, St. Marianna University School of Medicine, Miyamae-ku, Kawasaki, Japan.
  • Takahashi K; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
  • Ohtori S; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.
J Women Aging ; 33(3): 328-340, 2021.
Article em En | MEDLINE | ID: mdl-31770087
ABSTRACT
The aim of this study was to determine whether advanced glycation end products (AGEs) revealed by skin autofluorescence (SAF), serum and urine pentosidine level, and serum homocysteine level can serve as a biomarker for sarcopenia in older women. The participants were 70 elderly women. The AGEs pentosidine, homocysteine, and SAF were measured as aging markers. This study shows that among the biomarkers for aging, serum pentosidine correlates with a loss of appendicular lean mass and can serve as a biomarker for sarcopenia. Moreover, SAF and homocysteine values exhibited a positive correlation with age and correlated with each other.Abbreviations AGEs advanced glycation end products; BIA bioelectrical impedance analyzer; BMD bone mineral density; DLS degenerative lumbar scoliosis; DXA dual-energy X-ray absorptiometry; ELISA enzyme-linked immunoassay; HHcy hyperhomocysteinemia; RIA radioimmunoassay; SAF skin autofluorescence; SMI skeletal muscle mass index; T2DM type 2 diabetes patients.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Produtos Finais de Glicação Avançada / Diabetes Mellitus Tipo 2 / Sarcopenia Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Aged / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Produtos Finais de Glicação Avançada / Diabetes Mellitus Tipo 2 / Sarcopenia Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Aged / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article