Low prevalence of anti-hepatitis E virus IgG antibodies in Tepehuanos in Mexico.
Ann Hepatol
; 19(2): 186-189, 2020.
Article
em En
| MEDLINE
| ID: mdl-31771821
ABSTRACT
INTRODUCTION AND OBJECTIVE:
The epidemiology of infection with hepatitis E virus (HEV) in Tepehuanos (a Mexican ethnic group living in rural areas) is largely unknown. This study aimed to determine the seroprevalence of and risk factors associated with HEV infection in Tepehuanos in Durango, Mexico, and to compare this seroprevalence with that in non-Tepehuanos. MATERIALS ANDMETHODS:
Through a case-control seroprevalence study, we studied 146 Tepehuanos and 146 age- and gender-matched control subjects of the general population from rural settings. The frequency of anti-HEV IgG antibodies was determined using an enzyme-linked immunoassay. Bivariate and multivariate analyses were used to assess the association between seropositivity and socio-demographic, clinical and behavioral characteristics of the Tepehuanos.RESULTS:
IgG antibodies against HEV were found in 5 (3.4%; 95% CI 1.1-7.8) of 146 Tepehuanos and in 46 (31.5%; 95% CI 24.1-39.7) of 146 control subjects (OR=0.01; 95% CI 0.0007-0.20; P<0.000001). Bivariate analysis showed that HEV seropositivity was associated with age, consumption of meat from goat, sheep, boar, turkey and pigeon, and concrete flooring at home. However, these variables were no longer significant when analyzed by logistic regression.CONCLUSIONS:
This is first study on the epidemiology of HEV exposure in Tepehuanos. We demonstrated serological evidence of HEV infection in this ethnic group. The seroprevalence of HEV exposure in Tepehuanos is low as compared with that found in non-Tepehuano people living in rural Durango. Further studies to determine the risk factors associated with HEV exposure in Tepehuanos are needed.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
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Anticorpos Anti-Hepatite
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Vírus da Hepatite E
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Hepatite E
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Dieta
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Povos Indígenas
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Carne
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Animals
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Female
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Humans
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Male
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Middle aged
País como assunto:
Mexico
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article