The L-platform/L-scaffold framework: a blueprint for RNA-cleaving nucleic acid enzyme design.

Gaines, Colin S; Piccirilli, Joseph A; York, Darrin M

Gaines, Colin S; Piccirilli, Joseph A; York, Darrin M.

Afiliação

Gaines CS; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, USA.
Piccirilli JA; Department of Biochemistry and Molecular Biology and Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, USA.
York DM; Laboratory for Biomolecular Simulation Research, Institute for Quantitative Biomedicine, and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, USA.

RNA ; 26(2): 111-125, 2020 02.

Article em En | MEDLINE | ID: mdl-31776179

Assuntos

Engenharia Genética; Motivos de Nucleotídeos/genética; RNA Catalítico/genética; Catálise; Domínio Catalítico; Cátions Bivalentes/metabolismo; RNA/genética; RNA Catalítico/metabolismo

Palavras-chave

RNA catalysis; RNA motif; design; ontology; ribozyme engineering

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / RNA Catalítico / Motivos de Nucleotídeos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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