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CNS organoids: an innovative tool for neurological disease modeling and drug neurotoxicity screening.
Chhibber, Tanya; Bagchi, Sounak; Lahooti, Behnaz; Verma, Angela; Al-Ahmad, Abraham; Paul, Manash K; Pendyala, Gurudutt; Jayant, Rahul Dev.
Afiliação
  • Chhibber T; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA.
  • Bagchi S; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA.
  • Lahooti B; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA.
  • Verma A; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA.
  • Al-Ahmad A; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA.
  • Paul MK; Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USA.
  • Pendyala G; Department of Anesthesiology, College of Medicine, University of Nebraska Medical Center (UNMC), Omaha, NE 68198, USA.
  • Jayant RD; Department of Pharmaceutical Sciences, JH School of Pharmacy, Texas Tech University Health Sciences Center (TTUHSC), Amarillo, TX 79106, USA. Electronic address: rd.jayant@ttuhsc.edu.
Drug Discov Today ; 25(2): 456-465, 2020 02.
Article em En | MEDLINE | ID: mdl-31783130
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Organoides / Doenças do Sistema Nervoso Central / Síndromes Neurotóxicas / Avaliação Pré-Clínica de Medicamentos / Modelos Biológicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Organoides / Doenças do Sistema Nervoso Central / Síndromes Neurotóxicas / Avaliação Pré-Clínica de Medicamentos / Modelos Biológicos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article