ALK-negative anaplastic large cell lymphoma with "Hodgkin-like" cytomorphology and nuclear expression of PAX5.
Pathol Res Pract
; 216(2): 152724, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31784094
ABSTRACT
Anaplastic lymphoma kinase negative systemic anaplastic large cell lymphoma (ALK-ALCL) is a CD30+ T-cell malignant lymphoma which may involve both lymph nodes and extranodal tissues, showing important clinical differences from ALK-positive ALCL (ALKâ¯+â¯ALCL). ALK- ALCL is considered a specific entity by the 2016 World Health Organization (WHO) classification of hematolymphoid neoplasms.We describe an exceptional case of ALK- ALCL with a striking "Hodgkin-like" cytomorphology and a very uncommon nuclear expression of PAX5.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Linfoma Anaplásico de Células Grandes
/
Fator de Transcrição PAX5
Limite:
Aged80
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article