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Prognostic significance of platelet-to-lymphocyte ratio in patients with nasopharyngeal carcinoma: a meta-analysis.
Zhang, Junkai; Feng, Weineng; Ye, Zhihua; Wei, Ying; Li, Lamei; Yang, Yingyu.
Afiliação
  • Zhang J; Department I of Medical Oncology Center, Zhongshan Hospital of Sun Yat-sen University, People's Hospital of Zhongshan City, Zhongshan, Guangdong 528403, PR China.
  • Feng W; Department of Head & Neck/Thoracic Medical Oncology, The First People's Hospital of Foshan, Foshan, Guangdong 528000, PR China.
  • Ye Z; Department I of Medical Oncology Center, Zhongshan Hospital of Sun Yat-sen University, People's Hospital of Zhongshan City, Zhongshan, Guangdong 528403, PR China.
  • Wei Y; Department I of Medical Oncology Center, Zhongshan Hospital of Sun Yat-sen University, People's Hospital of Zhongshan City, Zhongshan, Guangdong 528403, PR China.
  • Li L; Department I of Medical Oncology Center, Zhongshan Hospital of Sun Yat-sen University, People's Hospital of Zhongshan City, Zhongshan, Guangdong 528403, PR China.
  • Yang Y; Department I of Medical Oncology Center, Zhongshan Hospital of Sun Yat-sen University, People's Hospital of Zhongshan City, Zhongshan, Guangdong 528403, PR China.
Future Oncol ; 16(5): 117-127, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31789058
ABSTRACT

Aim:

Several studies reported the association of platelet-to-lymphocyte ratio (PLR) and prognosis in nasopharyngeal carcinoma (NPC), but the results remain controversial. Therefore, we investigated the prognostic value of PLR in NPC through meta-analysis. Materials &

methods:

A comprehensive literature search of PubMed, Embase and Web of Science was performed.

Results:

A total of 9 studies comprising of 3459 patients with NPC were included. The data demonstrated that an increased PLR predicted poor overall survival, progression-free survival and distant metastasis-free survival. There was no significant association between PLR and sex, age, T stage, N stage, tumor node metastasis (TNM) stage or intensity-modulated radiotherapy.

Conclusion:

This meta-analysis revealed that PLR might be a potential predicative biomarker of poor prognosis in patients with NPC.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prognóstico / Plaquetas / Linfócitos / Carcinoma Nasofaríngeo Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prognóstico / Plaquetas / Linfócitos / Carcinoma Nasofaríngeo Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article