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Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.
Guillot, Adrien; Ren, Tianyi; Jourdan, Tony; Pawlosky, Robert J; Han, Elaine; Kim, Seung-Jin; Zhang, Li; Koob, George F; Gao, Bin.
Afiliação
  • Guillot A; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Ren T; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Jourdan T; Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Pawlosky RJ; Laboratory of Metabolic Control, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Han E; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Kim SJ; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Zhang L; Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892.
  • Koob GF; National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
  • Gao B; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892; bgao@mail.nih.gov.
Proc Natl Acad Sci U S A ; 116(51): 25974-25981, 2019 12 17.
Article em En | MEDLINE | ID: mdl-31792171
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Consumo de Bebidas Alcoólicas / Etanol / Aldeído-Desidrogenase Mitocondrial / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Consumo de Bebidas Alcoólicas / Etanol / Aldeído-Desidrogenase Mitocondrial / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article