Development of a Highly Efficient Hybrid Peptide That Increases Immunomodulatory Activity Via the TLR4-Mediated Nuclear Factor-&#954;B Signaling Pathway.

Zhang, Lulu; Wei, Xubiao; Zhang, Rijun; Koci, Matthew; Si, Dayong; Ahmad, Baseer; Cheng, Junhao; Wang, Junyong

Development of a Highly Efficient Hybrid Peptide That Increases Immunomodulatory Activity Via the TLR4-Mediated Nuclear Factor-κB Signaling Pathway.

Zhang, Lulu; Wei, Xubiao; Zhang, Rijun; Koci, Matthew; Si, Dayong; Ahmad, Baseer; Cheng, Junhao; Wang, Junyong.

Afiliação

Zhang L; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Wei X; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Zhang R; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Koci M; Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695, USA.
Si D; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Ahmad B; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Cheng J; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Wang J; Laboratory of Feed Biotechnology, State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Int J Mol Sci ; 20(24)2019 Dec 06.

Article em En | MEDLINE | ID: mdl-31817671

Assuntos

Fatores Imunológicos/síntese química; Fatores Imunológicos/farmacologia; Peptídeos/síntese química; Peptídeos/farmacologia; Animais; Western Blotting; Sobrevivência Celular/efeitos dos fármacos; Dicroísmo Circular; Ensaio de Imunoadsorção Enzimática; Feminino; Citometria de Fluxo; Fatores Imunológicos/química; Macrófagos Peritoneais/efeitos dos fármacos; Macrófagos Peritoneais/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Peptídeos/química; Células RAW 264.7

Palavras-chave

NF-κB; TLR4/MD-2; cyclophosphamide; immunoregulatory activity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Fatores Imunológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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