Impact of Candida auris Infection in a Neutropenic Murine Model.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Article
em En
| MEDLINE
| ID: mdl-31818824
Candida auris has become a global public health threat due to its multidrug resistance and persistence. Currently, there are limited murine models to study C. auris infection. Those models use a combination of cyclophosphamide and cortisone acetate, suppressing both innate and adaptive immunity. Here, we compare C. auris infection in two neutrophil-depleted murine models in which innate immunity is targeted using the monoclonal antibodies 1A8 and RB6-8C5.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Candida
/
Candidíase
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Cortisona
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Ciclofosfamida
Limite:
Animals
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article