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Impact of Candida auris Infection in a Neutropenic Murine Model.
Torres, Steven R; Pichowicz, Amber; Torres-Velez, Fernando; Song, Renjie; Singh, Navjot; Lasek-Nesselquist, Erica; De Jesus, Magdia.
Afiliação
  • Torres SR; Department of Biomedical Sciences, University at Albany, School of Public Health, Albany, New York, USA.
  • Pichowicz A; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
  • Torres-Velez F; College of Nursing and Health Sciences, University of Vermont, Burlington, Vermont, USA.
  • Song R; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
  • Singh N; Biochemistry and Immunology Core, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
  • Lasek-Nesselquist E; Applied Genomics Technology Core, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
  • De Jesus M; Center for Bioinformatics, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
Article em En | MEDLINE | ID: mdl-31818824
Candida auris has become a global public health threat due to its multidrug resistance and persistence. Currently, there are limited murine models to study C. auris infection. Those models use a combination of cyclophosphamide and cortisone acetate, suppressing both innate and adaptive immunity. Here, we compare C. auris infection in two neutrophil-depleted murine models in which innate immunity is targeted using the monoclonal antibodies 1A8 and RB6-8C5.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Candida / Candidíase / Cortisona / Ciclofosfamida Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Candida / Candidíase / Cortisona / Ciclofosfamida Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article