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Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts.
Mueller-Breckenridge, Alan J; Garcia-Alcalde, Fernando; Wildum, Steffen; Smits, Saskia L; de Man, Robert A; van Campenhout, Margo J H; Brouwer, Willem P; Niu, Jianjun; Young, John A T; Najera, Isabel; Zhu, Lina; Wu, Daitze; Racek, Tomas; Hundie, Gadissa Bedada; Lin, Yong; Boucher, Charles A; van de Vijver, David; Haagmans, Bart L.
Afiliação
  • Mueller-Breckenridge AJ; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland. alan_james.mueller-breckenridge@roche.com.
  • Garcia-Alcalde F; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Wildum S; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Smits SL; Department of Viroscience, Erasmus Medical Center, Rotterdam, 's-Gravendijkwal 230, 3015 CE, Rotterdam, Netherlands.
  • de Man RA; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • van Campenhout MJH; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Brouwer WP; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Niu J; Zhongshan Hospital Xiamen University, 205 Hubin S Rd, Siming Qu, Xiamen, 361000, Fujian, China.
  • Young JAT; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Najera I; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Zhu L; Roche Innovation Centre Shanghai, Roche R&D Centre (China) Ltd., 720 Cai Lun Road, Pudong, Shanghai, 201203, China.
  • Wu D; Roche Innovation Centre Shanghai, Roche R&D Centre (China) Ltd., 720 Cai Lun Road, Pudong, Shanghai, 201203, China.
  • Racek T; Roche Innovation Centre, Basel, Switzerland F. Hoffmann-La Roche AG, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.
  • Hundie GB; Department of Viroscience, Erasmus Medical Center, Rotterdam, 's-Gravendijkwal 230, 3015 CE, Rotterdam, Netherlands.
  • Lin Y; Zhongshan Hospital Xiamen University, 205 Hubin S Rd, Siming Qu, Xiamen, 361000, Fujian, China.
  • Boucher CA; Department of Viroscience, Erasmus Medical Center, Rotterdam, 's-Gravendijkwal 230, 3015 CE, Rotterdam, Netherlands.
  • van de Vijver D; Department of Viroscience, Erasmus Medical Center, Rotterdam, 's-Gravendijkwal 230, 3015 CE, Rotterdam, Netherlands.
  • Haagmans BL; Department of Viroscience, Erasmus Medical Center, Rotterdam, 's-Gravendijkwal 230, 3015 CE, Rotterdam, Netherlands. b.haagmans@erasmusmc.nl.
Sci Rep ; 9(1): 18892, 2019 12 11.
Article em En | MEDLINE | ID: mdl-31827222

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / DNA Viral / Vírus da Hepatite B / Genoma Viral / Hepatite B Crônica / Aprendizado de Máquina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / DNA Viral / Vírus da Hepatite B / Genoma Viral / Hepatite B Crônica / Aprendizado de Máquina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article