A 13-Week Repeated Oral Dose Toxicity Study of ChondroT in Sprague-Dawley Rats.

Jeong, Jiwon; Bae, Kiljoon; Kim, Jihoon; Choi, Chanhun; Na, Changsu; Park, Myeongkyu; Kim, Youngran; Seo, Chang-Seob; Kim, Seon-Jong

Jeong, Jiwon; Bae, Kiljoon; Kim, Jihoon; Choi, Chanhun; Na, Changsu; Park, Myeongkyu; Kim, Youngran; Seo, Chang-Seob; Kim, Seon-Jong.

Afiliação

Jeong J; Yeongam Public Health Center, 39 Orijeong-gil, Yeongam, 58421, Jeollanam-do, Republic of Korea.
Bae K; Department of Korean Medical Rehabilitation, Kwangju Korean Medicine Hospital of Dongshin University, 313 Baengnyeondae-ro, Mokpo, 58665, Jeollanam-do, Republic of Korea.
Kim J; College of Korean Medicine, Dongshin University, 185 Geonjae-ro, Naju, 58245, Jeollanam-do, Republic of Korea.
Choi C; College of Korean Medicine, Dongshin University, 185 Geonjae-ro, Naju, 58245, Jeollanam-do, Republic of Korea.
Na C; College of Korean Medicine, Dongshin University, 185 Geonjae-ro, Naju, 58245, Jeollanam-do, Republic of Korea.
Park M; Healthcare Research Institute, Korea Testing and Research Institute (KTR), 12-63 Sandan-gil, Hwasun, 58141, Jeollanam-do, Republic of Korea.
Kim Y; College of Pharmacy, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea.
Seo CS; Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon, 34054, Republic of Korea.
Kim SJ; College of Korean Medicine, Dongshin University, 185 Geonjae-ro, Naju, 58245, Jeollanam-do, Republic of Korea. mofoster@hanmail.net.

BMC Complement Altern Med ; 19(1): 367, 2019 Dec 12.

Article em En | MEDLINE | ID: mdl-31830971

Assuntos

Extratos Vegetais/toxicidade; Testes de Toxicidade Subcrônica; Administração Oral; Animais; Peso Corporal/efeitos dos fármacos; Feminino; Masculino; Tamanho do Órgão/efeitos dos fármacos; Extratos Vegetais/administração & dosagem; Próstata/efeitos dos fármacos; Próstata/patologia; Ratos; Ratos Sprague-Dawley; Glândula Submandibular/efeitos dos fármacos; Glândula Submandibular/patologia; Testículo/efeitos dos fármacos; Testículo/patologia

Palavras-chave

13-week repeated oral dose toxicity; 4-week recovery test; ChondroT; NOAEL

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Testes de Toxicidade Subcrônica Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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