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Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening.
Sanchez, Mateo I; de Vries, Laura E; Lehmann, Christine; Lee, Jeong T; Ang, Kenny K; Wilson, Christopher; Chen, Steven; Arkin, Michelle R; Bogyo, Matthew; Deu, Edgar.
Afiliação
  • Sanchez MI; Departments of Pathology and Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, United States of America.
  • de Vries LE; Chemical Biology Approaches to Malaria Lab, The Francis Crick Institute, London, United Kingdom.
  • Lehmann C; Chemical Biology Approaches to Malaria Lab, The Francis Crick Institute, London, United Kingdom.
  • Lee JT; Departments of Pathology and Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, United States of America.
  • Ang KK; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, United States of America.
  • Wilson C; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, United States of America.
  • Chen S; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, United States of America.
  • Arkin MR; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, United States of America.
  • Bogyo M; Departments of Pathology and Microbiology & Immunology, Stanford School of Medicine, Stanford, CA, United States of America.
  • Deu E; Chemical Biology Approaches to Malaria Lab, The Francis Crick Institute, London, United Kingdom.
PLoS One ; 14(12): e0226270, 2019.
Article em En | MEDLINE | ID: mdl-31851699
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Inibidores de Cisteína Proteinase / Proteínas de Protozoários / Dipeptidil Peptidases e Tripeptidil Peptidases / Cisteína Proteases / Antimaláricos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Inibidores de Cisteína Proteinase / Proteínas de Protozoários / Dipeptidil Peptidases e Tripeptidil Peptidases / Cisteína Proteases / Antimaláricos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article