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Site-Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding.
Haj-Yahya, Mahmood; Gopinath, Pushparathinam; Rajasekhar, Kolla; Mirbaha, Hilda; Diamond, Marc I; Lashuel, Hilal A.
Afiliação
  • Haj-Yahya M; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
  • Gopinath P; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
  • Rajasekhar K; Current Address: Department of Chemistry, SRM Institute of Science and Technology, Chennai, TamilNadu, India.
  • Mirbaha H; Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Faculty of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
  • Diamond MI; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Lashuel HA; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Angew Chem Int Ed Engl ; 59(10): 4059-4067, 2020 03 02.
Article em En | MEDLINE | ID: mdl-31863676
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas tau / Microtúbulos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas tau / Microtúbulos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article