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Risk factors of severe hand, foot and mouth disease in Shantou, China: a case-control study.
Liu, Chunhua; Wang, Kaiyan; Lin, Niyang; Cai, Jianling; Cui, Binglin; Wu, Beiyan.
Afiliação
  • Liu C; The First Affiliated Hospital of Shantou University Medical College, Shantou, China. chliu@stu.edu.cn.
  • Wang K; Shantou University Medical College , Shantou, China. stwangkaiyan@hotmail.com.
  • Lin N; The First Affiliated Hospital of Shantou University Medical College, Shantou, China. stlinniyang@hotmail.com.
  • Cai J; The First Affiliated Hospital of Shantou University Medical College, Shantou, China. stjianlingcai@yeah.net.
  • Cui B; The First Affiliated Hospital of Shantou University Medical College, Shantou, China. stbinglincui@163.com.
  • Wu B; The First Affiliated Hospital of Shantou University Medical College, Shantou, China. stwubeiyan@163.com.
J Infect Dev Ctries ; 12(5): 359-364, 2018 May 31.
Article em En | MEDLINE | ID: mdl-31865299
INTRODUCTION: In clinical perspectives, how to distinguish a small proportion of children at risk of developing neurological complications from a large number of children with mild symptoms still remains a challenge for primary care doctors. METHODOLOGY: From January 2012 to December 2015, 225 cases with severe hand, foot and mouth disease (HFMD) matched with 492 controls were enrolled in the age-matched, case-control study. Continuous variables were examined by univariate analysis using a chi-squared or Fisher's exact test, and categorical variables were reported by relative risks (odd's ratio). Multivariate logistic regression was used to analyze the independent risk factors for severe HFMD. RESULTS: Peak body temperature over 37.5℃,total duration of fever over 3 days, lethargy, enterovirus 71 (EV71) infection were independent risk factors for severe HFMD. CONCLUSIONS: Peak body temperature over 37.5℃,total duration of fever over 3 days, lethargy, EV71 infection were independent risk factors for severe HFMD.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article