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A novel phytosterol isolated from Datura inoxia, RinoxiaB is a potential cure colon cancer agent by targeting BAX/Bcl2 pathway.
Gajendran, Babu; Durai, Prabhu; Madhu Varier, Krishnapriya; Chinnasamy, Arulvasu.
Afiliação
  • Gajendran B; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, Guizhou Province, People's Republic of China; Key Laboratory of Chemistry for Natural Pro
  • Durai P; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India.
  • Madhu Varier K; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India; Department of Medical Biochemistry, Dr. ALM PGIBMS, University of Madras, Taramani Campus, Chennai 600113, Tamil Nadu, India.
  • Chinnasamy A; Department of Zoology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India. Electronic address: carulvasu@gmail.com.
Bioorg Med Chem ; 28(2): 115242, 2020 01 15.
Article em En | MEDLINE | ID: mdl-31866271
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fitosteróis / Extratos Vegetais / Neoplasias do Colo / Proteínas Proto-Oncogênicas c-bcl-2 / Datura / Proteína X Associada a bcl-2 / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fitosteróis / Extratos Vegetais / Neoplasias do Colo / Proteínas Proto-Oncogênicas c-bcl-2 / Datura / Proteína X Associada a bcl-2 / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article