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AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis.
Bisserier, Malik; Milara, Javier; Abdeldjebbar, Yassine; Gubara, Sarah; Jones, Carly; Bueno-Beti, Carlos; Chepurko, Elena; Kohlbrenner, Erik; Katz, Michael G; Tarzami, Sima; Cortijo, Julio; Leopold, Jane; Hajjar, Roger J; Sassi, Yassine; Hadri, Lahouaria.
Afiliação
  • Bisserier M; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Milara J; Health Research Institute INCLIVA, Valencia, Spain; Pharmacy Unit, University Clinic Hospital, Valencia, Spain; CIBERES, Health Institute Carlos III, Valencia, Spain.
  • Abdeldjebbar Y; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Gubara S; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Jones C; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Bueno-Beti C; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Chepurko E; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Kohlbrenner E; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Katz MG; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Tarzami S; Department of Physiology and Biophysics, College of Medicine, Howard University, Washington, DC, USA.
  • Cortijo J; Health Research Institute INCLIVA, Valencia, Spain; Pharmacy Unit, University Clinic Hospital, Valencia, Spain; CIBERES, Health Institute Carlos III, Valencia, Spain.
  • Leopold J; Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Hajjar RJ; Phospholamban Foundation, Amsterdam, Netherlands.
  • Sassi Y; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Hadri L; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: lahouaria.hadri@mssm.edu.
Mol Ther ; 28(2): 394-410, 2020 02 05.
Article em En | MEDLINE | ID: mdl-31879190
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Terapia Genética / Transdução de Sinais / Dependovirus / ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático / Vetores Genéticos Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Terapia Genética / Transdução de Sinais / Dependovirus / ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático / Vetores Genéticos Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article