Photocatalytic Isocyanide-Based Multicomponent Domino Cascade toward the Stereoselective Formation of Iminofurans.
J Org Chem
; 85(4): 1981-1990, 2020 02 21.
Article
em En
| MEDLINE
| ID: mdl-31880934
ABSTRACT
A visible-light-promoted three-component isocyanide-based synthesis of iminofurans is herein reported. The reaction proved to be general in scope and proceeds through a triple domino process. Control experiments with 18O-labeled water and TEMPO provided key mechanistic insights for delineating the reactivity paradigms crucial to design efficient photoredox isocyanide-based domino transformations.
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MEDLINE
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article