Mycobacterium tuberculosis clinical isolates of the Beijing and East-African Indian lineage induce fundamentally different host responses in mice compared to H37Rv.

Mourik, Bas C; de Steenwinkel, Jurriaan E M; de Knegt, Gerjo J; Huizinga, Ruth; Verbon, Annelies; Ottenhoff, Tom H M; van Soolingen, Dick; Leenen, Pieter J M

Mourik, Bas C; de Steenwinkel, Jurriaan E M; de Knegt, Gerjo J; Huizinga, Ruth; Verbon, Annelies; Ottenhoff, Tom H M; van Soolingen, Dick; Leenen, Pieter J M.

Afiliação

Mourik BC; Department Medical Microbiology & Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands.
de Steenwinkel JEM; Department Medical Microbiology & Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands.
de Knegt GJ; Department Medical Microbiology & Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands.
Huizinga R; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Verbon A; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
van Soolingen D; National Tuberculosis Reference Laboratory, National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Leenen PJM; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands. p.leenen@erasmusmc.nl.

Sci Rep ; 9(1): 19922, 2019 12 27.

Article em En | MEDLINE | ID: mdl-31882653

Assuntos

Mycobacterium tuberculosis/patogenicidade; Animais; Medula Óssea/metabolismo; China; Feminino; Interferon gama/metabolismo; Interleucina-4/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Mycobacterium tuberculosis/metabolismo; Reação em Cadeia da Polimerase em Tempo Real; Linfócitos T/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Virulência

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals País como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google