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Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics.
East, Kyle W; Newton, Jocelyn C; Morzan, Uriel N; Narkhede, Yogesh B; Acharya, Atanu; Skeens, Erin; Jogl, Gerwald; Batista, Victor S; Palermo, Giulia; Lisi, George P.
Afiliação
  • East KW; Department of Molecular Biology, Cell Biology & Biochemistry , Brown University , Providence , Rhode Island 02903 , United States.
  • Newton JC; Department of Molecular Biology, Cell Biology & Biochemistry , Brown University , Providence , Rhode Island 02903 , United States.
  • Morzan UN; Department of Chemistry , Yale University , New Haven , Connecticut 06520 , United States.
  • Narkhede YB; Department of Bioengineering , University of California Riverside , 900 University Avenue , Riverside , California 92512 , United States.
  • Acharya A; Department of Chemistry , Yale University , New Haven , Connecticut 06520 , United States.
  • Skeens E; Department of Molecular Biology, Cell Biology & Biochemistry , Brown University , Providence , Rhode Island 02903 , United States.
  • Jogl G; Department of Molecular Biology, Cell Biology & Biochemistry , Brown University , Providence , Rhode Island 02903 , United States.
  • Batista VS; Department of Chemistry , Yale University , New Haven , Connecticut 06520 , United States.
  • Palermo G; Department of Bioengineering , University of California Riverside , 900 University Avenue , Riverside , California 92512 , United States.
  • Lisi GP; Department of Molecular Biology, Cell Biology & Biochemistry , Brown University , Providence , Rhode Island 02903 , United States.
J Am Chem Soc ; 142(3): 1348-1358, 2020 01 22.
Article em En | MEDLINE | ID: mdl-31885264

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ressonância Magnética Nuclear Biomolecular / Simulação de Dinâmica Molecular / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ressonância Magnética Nuclear Biomolecular / Simulação de Dinâmica Molecular / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2020 Tipo de documento: Article