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An anticancer gold(III)-activated porphyrin scaffold that covalently modifies protein cysteine thiols.
Tong, Ka-Chung; Lok, Chun-Nam; Wan, Pui-Ki; Hu, Di; Fung, Yi Man Eva; Chang, Xiao-Yong; Huang, Song; Jiang, Haibo; Che, Chi-Ming.
Afiliação
  • Tong KC; State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Hong Kong, China.
  • Lok CN; Laboratory for Synthetic Chemistry and Chemical Biology, Health@InnoHK, Hong Kong, China.
  • Wan PK; State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Hong Kong, China.
  • Hu D; Laboratory for Synthetic Chemistry and Chemical Biology, Health@InnoHK, Hong Kong, China.
  • Fung YME; State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Hong Kong, China.
  • Chang XY; Laboratory for Synthetic Chemistry and Chemical Biology, Health@InnoHK, Hong Kong, China.
  • Huang S; State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Hong Kong, China.
  • Jiang H; Laboratory for Synthetic Chemistry and Chemical Biology, Health@InnoHK, Hong Kong, China.
  • Che CM; State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Hong Kong, China.
Proc Natl Acad Sci U S A ; 117(3): 1321-1329, 2020 01 21.
Article em En | MEDLINE | ID: mdl-31896586
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Ouro / Mesoporfirinas / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Ouro / Mesoporfirinas / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article